Mycoplasma felis is a natural part of the cat's normal bacterial flora (microbiota), but can also cause symptoms of infection, especially milder eye infections in the form of conjunctivitis (conjunctivitis). Mycoplasma felis should not be confused with Mycoplasma haemofelis which specifically causes anemia (lack of blood) in cats.

The two main causes of eye infection in cats are Chlamydia felis and feline herpesvirus (FHV-1). The two infections can each cause anywhere from no symptoms to mild to very severe symptoms. As a rule, Mycoplama felis does not cause more serious problems or any problems at all. A cat with a more serious eye infection and a test result where Mycoplasma felis is found may have underlying problems that "help" the bacteria to cause the symptoms, for example, co-infection with Chlamydia felis and/or feline herpes virus.

The bacterium Mycoplasma felis is part of the cat's normal bacterial flora (microbiota). This means that it is often found in healthy cats in the eyes and upper respiratory tracts such as the nose, mouth, and throat without causing any problems. Typically conjunctivitis is seen. The problems are usually not serious, but treatment may be necessary in this case.